Stochastic models for chemical and biochemical reactions have been around for a long time. The standard algorithm for simulating the dynamics of such processes on a computer (the ‘Gillespie algorithm’) was published nearly 30 years ago (and most of the relevant theory was sorted out long before that). In the meantime there have been dozens of papers published on stochastic kinetics, and several books on stochastic processes in physics, chemistry, and biology. Biological modelling and biochemical kinetic modelling have been around even longer. These distinct subjects have started to merge in recent years as technology has begun to give real insight into intra-cellular processes. Improvements in experimental technology ...
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