Temperature-Responsive Polymers

Temperature-Responsive Polymers

by Vitaliy V. Khutoryanskiy, Theoni K. Georgiou
Released August 2018
Publisher(s): Wiley
ISBN: 9781119157786

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Book description

An authoritative resource that offers an understanding of the chemistry, properties and applications of temperature-responsive polymers

With contributions from a distinguished panel of experts, Temperature-Responsive Polymers puts the focus on hydrophilic polymers capable of changing their physicochemical properties in response to changes in environmental temperature. The contributors review the chemistry of these systems, and discuss a variety of synthetic approaches for preparation of temperature-responsive polymers, physicochemical methods of their characterisation and potential applications in biomedical areas.

The text reviews a wide-variety of topics including: The characterisation of temperature-responsive polymers; Infrared and Raman spectroscopy; Applications of temperature-responsive polymers grafted onto solid core nanoparticles; and much more. The contributors also explore how temperature-responsive polymers can be used in the biomedical field for applications such as tissue engineering. This important resource:

  • Offers an important synthesis of the current research on temperature-responsive polymers
  • Covers the chemistry, the synthetic approaches for presentation and the physiochemical method of temperature-responsive polymers
  • Includes a review of the fundamental characteristics of temperature-responsive polymers
  • Explores many of the potential applications in biomedical science, including drug delivery and gene therapy

Written for polymer scientists in both academia and industry as well as postgraduate students working in the area of stimuli-responsive materials, this vital text offers an exploration of the chemistry, properties and current applications of temperature-responsive polymers.

Table of contents

  1. Cover
  2. Copyright
  3. About the Editors
  4. List of Contributors
  5. Preface
    1. References
  6. Part I: Chemistry
    1. Chapter 1: Poly(N‐isopropylacrylamide): Physicochemical Properties and Biomedical Applications
      1. 1.1 Introduction
      2. 1.2 PNIPAM as Thermosensitive Polymer
      3. 1.3 Physical Properties of PNIPAM
      4. 1.4 Common Methods for Polymerization of NIPAM
      5. 1.5 Dual Sensitive Systems
      6. 1.6 Bioconjugation of PNIPAM
      7. 1.7 Liposome Surface Modification with PNIPAM
      8. 1.8 Applications of PNIPAM in Cell Culture
      9. 1.9 Crosslinking Methods for Polymers
      10. 1.10 Conclusion and Outlook of Applications of PNIPAM
      11. Acknowledgments
      12. References
    2. Chapter 2: Thermoresponsive Multiblock Copolymers: Chemistry, Properties and Applications
      1. 2.1 Introduction
      2. 2.2 Chemistry of Thermoresponsive Block‐based Copolymers
      3. 2.3 Architecture, Number of Blocks and Block Sequence
      4. 2.4 Applications
      5. 2.5 Conclusions
      6. Acknowledgments
      7. References
    3. Chapter 3: Star‐shaped Poly(2‐alkyl‐2‐oxazolines): Synthesis and Properties
      1. 3.1 Introduction
      2. 3.2 Synthesis of Star‐shaped Poly(2‐alkyl‐2‐oxazolines)
      3. 3.3 Properties of Star‐shaped Poly(2‐alkyl‐2‐oxazolines)
      4. 3.4 Conclusions
      5. References
    4. Chapter 4: Poly(N‐vinylcaprolactam): From Polymer Synthesis to Smart Self‐assemblies
      1. 4.1 Introduction
      2. 4.2 Synthesis of PVCL Homo‐ and Copolymers
      3. 4.3 Properties of PVCL in Aqueous Solutions
      4. 4.4 Assembly of PVCL‐based Polymers in Solution
      5. 4.5 Templated Assemblies of PVCL Polymers
      6. 4.6 Outlook and Perspectives
      7. Acknowledgment
      8. References
    5. Chapter 5: Sodium Alginate Grafted with Poly(N‐isopropylacrylamide)
      1. 5.1 Alginic Acid
      2. 5.2 Poly(N‐Isopropylacrylamide) and Thermoresponsive Properties
      3. 5.3 Synthesis and Characterization of Alginate‐graft‐PNIPAM Copolymers
      4. 5.4 Solution Properties
      5. 5.5 Conclusions and Perspectives
      6. References
    6. Chapter 6: Multi‐stimuli‐responsive Polymers Based on Calix[4]arenes and Dibenzo‐18‐crown‐6‐ethers
      1. 6.1 Introduction
      2. 6.2 Single‐stimuli‐responsive Polymers
      3. 6.3 Multi‐stimuli‐responsive Polymers
      4. 6.4 Poly(azocalix[4]arene)s and Poly(azodibenzo‐18‐crown‐6‐ether)s
      5. 6.5 Photoisomerization
      6. 6.6 Host–guest Interactions
      7. 6.7 Thermo‐responsiveness
      8. 6.8 Solvatochromism and pH Sensitivity
      9. 6.9 Summary and Outlook
      10. Acknowledgments
      11. References
  7. Part II: Characterization of Temperature‐responsive Polymers
    1. Chapter 7: Small‐Angle X‐ray and Neutron Scattering of Temperature‐Responsive Polymers in Solutions
      1. 7.1 Introduction
      2. 7.2 Temperature‐responsive Homopolymers
      3. 7.3 Hydrophobically Modified Polymers
      4. 7.4 Cross‐Linked Temperature‐Sensitive Polymers and Gels
      5. 7.5 Temperature‐Responsive Block Copolymers
      6. 7.6 Hybrid Nanoparticles
      7. 7.7 Gradient Temperature‐Responsive Polymers
      8. 7.8 Multi‐responsive Copolymers
      9. 7.9 Concluding Remarks
      10. Acknowledgments
      11. References
    2. Chapter 8: Infrared and Raman Spectroscopy of Temperature‐Responsive Polymers
      1. 8.1 Introduction
      2. 8.2 Experimental Methods to Measure IR and Raman Spectra of Aqueous Solutions
      3. 8.3 Poly(N‐substituted acrylamide)s
      4. 8.4 Poly(vinyl ether)s
      5. 8.5 Poly(meth)acrylates
      6. 8.6 Effects of Additives on Phase Behavior
      7. 8.7 Temperature‐Responsive Copolymers and Gels
      8. References
    3. Chapter 9: Application of NMR Spectroscopy to Study Thermoresponsive Polymers
      1. 9.1 Introduction
      2. 9.2 Coil–Globule Phase Transition and Its Manifestation in NMR Spectra
      3. 9.3 Temperature Dependences of High‐Resolution NMR Spectra: Phase‐Separated Fraction p
      4. 9.4 Multicomponent Polymer Systems
      5. 9.5 Effects of Low‐Molecular‐Weight Additives on Phase Transition
      6. 9.6 Behavior of Water at the Phase Transition
      7. 9.7 Conclusion
      8. Acknowledgment
      9. References
    4. Chapter 10: Polarized Luminescence Studies of Nanosecond Dynamics of Thermosensitive Polymers in Aqueous Solutions
      1. 10.1 Introduction
      2. 10.2 Theoretical Part
      3. 10.3 Experimental Part
      4. 10.4 Conclusion
      5. References
  8. Part III: Applications of Temperature‐responsive Polymers
    1. Chapter 11: Applications of Temperature‐Responsive Polymers Grafted onto Solid Core Nanoparticles
      1. 11.1 Introduction
      2. 11.2 Silica Nanoparticles
      3. 11.3 Metallic Nanoparticles
      4. 11.4 Magnetic Nanoparticles
      5. 11.5 Conclusions
      6. References
    2. Chapter 12: Temperature‐responsive Polymers for Tissue Engineering
      1. 12.1 Introduction
      2. 12.2 Conclusions
      3. Acknowledgments
      4. References
    3. Chapter 13: Thermogel Polymers for Injectable Drug Delivery Systems
      1. 13.1 Introduction
      2. 13.2 Pluronics®
      3. 13.3 Polyester‐based Polymers
      4. 13.4 Chitosan and Derivatives
      5. 13.5 Polypeptides
      6. 13.6 Clinical Application of Thermogel Polymers
      7. 13.7 Summary
      8. References
    4. Chapter 14: Thermoresponsive Electrospun Polymer‐based (Nano)fibers
      1. 14.1 Introduction
      2. 14.2 Basic Principles of Electrospinning
      3. 14.3 PNIPAM‐based Electrospun (Nano)fibers
      4. 14.4 Other Types of Thermoresponsive Electrospun (Nano)fibers
      5. 14.5 Conclusions and Outlook
      6. References
    5. Chapter 15: Catalysis by Thermoresponsive Polymers
      1. 15.1 Introduction
      2. 15.2 Metal Complexes Immobilized Within Thermosensitive Polymers
      3. 15.3 Thermoresponsive Polyampholytes
      4. 15.4 Thermosensitive Hydrogels in Catalysis
      5. 15.5 Thermoresponsive Catalytically Active Nano‐ and Microgels, Spheres, Capsules, and Micelles
      6. 15.6 Thermosensitive Self‐Assemblies
      7. 15.7 Mono‐ and Bimetallic Nanoparticles Stabilized by Thermoresponsive Polymers
      8. 15.8 Enzymes‐Embedded Thermoresponsive Polymers
      9. 15.9 Immobilization of Magnetic Nanoparticles into the Matrix of Thermoresponsive Polymers for Efficient Separation of Catalysts
      10. 15.10 Summary
      11. Acknowledgments
      12. References
  9. Index
  10. End User License Agreement

Product information

  • Title: Temperature-Responsive Polymers
  • Author(s): Vitaliy V. Khutoryanskiy, Theoni K. Georgiou
  • Release date: August 2018
  • Publisher(s): Wiley
  • ISBN: 9781119157786