Chapter 23
Nonlinear Designs
When the goal of your experiment is to fit a model that is nonlinear in the unknown parameters, use a nonlinear design to place design points in areas that are key to fitting the nonlinear model. Although you could use an orthogonal design that is optimal for a linear model, such designs, in general, do not place design points in locations that minimize the uncertainty (or maximize the precision) of the estimates of the fitted parameters.
The efficiency of a nonlinear design depends on the values of the unknown parameters. This creates a circular problem in that to find the best design, you need to know the parameters in advance. JMP uses a Bayesian approach to construct a nonlinear design that maximizes the average ...
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