Pharmaceutics

8

Sterile Dosage Forms

INTRODUCTION

Learning Objective

• Introduction and classification of sterile dosage forms
• Different routes of injection administration

Sterile, pyrogen-free preparations intended to be administered by way of injections are called parenterals. The term “parenteral” is derived from the Greek terms para (outside or other than) and enteron (intestine) and denotes routes of administration other than the oral route.

The various sterile dosage forms are small and large volume injectables, irrigation fluids, dialysis solutions, biological preparations including vaccines, toxoids, antitoxins and ophthalmic preparations. Sterility is a prerequisite for parenterals because these preparations come into direct contact with the internal ...