Key Barrier: Organizational—Misalignment, Fragmentation, and Legacy ThinkingKey Barrier: Technological—Complexity, Interoperability, and SecurityKey Barrier: Human and Workforce—Skills, Culture, and TrustKey Barrier: Financial—Cost, ROI Uncertainty, and Risk AversionDecision-Making Framework for Barriers and Industry 5.0Navigating the Human Side of Digital Supply Chain TransformationConclusionReferences