17 Vibro‐acoustography and its Medical Applications
Azra Alizad1 and Mostafa Fatemi2
1 Department of Radiology, Mayo Clinic, Rochester, MN, USA
2 Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN, USA
17.1 Introduction
Vibro‐acoustography (VA), a new ultrasound‐based imaging modality, has gained much interest in the medical field in recent years. This acoustic imaging modality uses the radiation force of ultrasound to induce low‐frequency vibrations in the tissue and creates images of the acoustic response. This chapter focuses on potential biomedical applications of VA. The purpose is to bring together the results of various studies, ex vivo and in vivo, on breast, thyroid, human arteries, and prostate. Here, after a brief discussion about the general principle of VA, we describe the applications. Future developments and potential impact of VA in breast and thyroid imaging are also discussed.
17.2 Background
New imaging modalities based on radiation force of ultrasound have been developed for characterizing mechanical properties of soft tissues. All of these methods aim to differentiate normal tissue from diseased tissue by exploiting the elasticity as a contrast mechanism. Ultrasound radiation force vibrates and deforms soft tissues noninvasively, and the resulting mechanical response of tissues provides elasticity information useful in detection and differentiation.
17.2.1 General Principles of VA and Method
VA is a noninvasive ...
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