2Introduction to Bioinformatics
Bancha Yingngam
Department of Pharmaceutical Chemistry and Technology, Faculty of Pharmaceutical Sciences, Ubon Ratchathani University, Ubon Ratchathani, Thailand
Abstract
Bioinformatics is a crucial interdisciplinary field intersecting biology, computer science, and statistics. It acts as a pivotal catalyst in transforming life sciences and biomedical research. Despite its importance, the field grapples with issues such as overwhelming biological data volumes, inconsistent data handling standards, and a dearth of experts skilled in all intersecting disciplines. These challenges permeate academia, the pharmaceutical industry, and public health, affecting advancements in biological research, personalized medicine, and disease outbreak understanding. The chapter aims to offer an in-depth review of bioinformatics, covering its definition, significance, and inherent challenges. It intends to elevate the reader’s scientific contextual understanding by detailing frequently used tools and resources, such as sequence alignment, gene and protein prediction, protein structure modeling, and complex genomic data analysis. The chapter also critically evaluates existing limitations, including data integration hurdles and the urgent need for advanced computational methods. Conclusively, it paints an optimistic picture of the future of this rapidly evolving field, highlighting the potential for breakthroughs that could profoundly enhance our understanding of ...
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