August 2012
Intermediate to advanced
360 pages
12h 11m
English
Content preview from Biosensors for Medical Applications
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9
Biosensors for drug testing and discovery
C. Parsajoo and J-M. Kauffmann, Université libre de Bruxelles, Belgium
M. Elkaoutit, Universidad de Cádiz, Spain
Abstract:
In this chapter, electrochemical, optical, and acoustic biosensors are reviewed, in a non-exhaustive manner, for the investigation of some drug compounds. Biosensors provide an original conceptual approach as a measuring tool ‘decorated’ by a biological element. Applications to the quantitative determination of a drug compound in pharmaceutical formulations are described but the preferred field of application is monitoring of the interaction strength of the studied pharmacologically active molecule with the immobilised biocomponent. Enzymes, antibodies, oligonucleotides, ...
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