18Handwriting Analysis for Early Detection of Alzheimer's Disease
Rajib Saha1, Anirban Mukherjee1, Aniruddha Sadhukhan1, Anisha Roy1, and Manashi De3
1Department of Computer Science & Engineering, RCC Institute of Information Technology, West Bengal, India
2Department of Information Technology, RCC Institute of Information Technology, West Bengal, India
3Department of Computer Science & Engineering, Salt Lake, West Bengal, India
18.1 Introduction and Background
The umbrella term “neurodegenerative disease (NGD)” is used to refer to conditions that primarily affect the neurons in the human brain. The peripheral nervous system with the muscles, nerve junctions, spinal cord, and motor nerve cells are affected by NGD. The nervous system, including the brain and spinal cord is made of neuron that cannot be reproduced or replaced by the body once they are damaged. Therefore these diseases are incurable. These diseases result in a condition that causes the nerve cells to become progressively damaged and/or die. These damaged or dead neurons are unable to perform efficiently, leading to problems in movement (called ataxias), or mental functioning (called dementias) in patients. Once the disease has progressed beyond a certain level, impairment of cognitive and functional abilities is observed. Behavioral changes are also prevalent in many cases. Based on the type of NGD, currently the most useful and reliable tools for diagnosing NGD are magnetic resonance imagings (MRIs), lumbar puncture ...
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