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Nanotechnology in Cancer

Book Description

Nanotechnology in Cancer covers current nanotechnology-based nanotherapeutics involving gold nanoparticles, colloids, gels, magnetic nanoparticles, radiofrequency, gene therapy, biological particles, and the intermolecular interactions associated with nanoparticle based cancer therapy in vivo.

Different cancer types and locations are considered alongside the corresponding treatment types, and the use of imaging technologies and animal models are also explored. Both scientific and clinical aspects are considered by authors coming from both fields, with the authors using their backgrounds from different disciplines to make the connection between cancer and effective drug delivery and therapeutic strategies.

  • Authored by leaders from the scientific research and clinical communities who use their background from different disciplines to explore the connections between cancer and effective drug delivery and therapeutic strategies
  • Brings together tumor biology, imaging technologies, nanomaterial platforms for drug delivery, therapeutic strategies, and reconstructive surgery
  • Explores the clinical and regulatory challenges facing nanomedicine

Table of Contents

  1. Cover image
  2. Title page
  3. Table of Contents
  4. Copyright
  5. Contributors
  6. About the Authors
  7. Foreword
  8. Preface
  9. Introduction to Bio-Nanotechnology
  10. Chapter 1. Gold nanoparticles for noninvasive radiofrequency cancer hyperthermia
    1. Abstract
    2. Introduction
    3. Brief Overview of Clinically Available Hyperthermia Systems
    4. Nanoparticle-Mediated Cancer Hyperthermia
    5. RF Interactions With AuNPs
    6. Theoretical Frameworks for RF-Induced AuNP Heating
    7. Biological RF Activity of AuNPs In Vitro/In Vivo
    8. Conclusion
    9. References
  11. Chapter 2. Silk fibroin nanoparticles and cancer therapy
    1. Abstract
    2. Introduction
    3. Materials and Methods
    4. Results
    5. Discussion
    6. Conclusions
    7. Acknowledgments
    8. References
  12. Chapter 3. Animal models in cancer nanotechnology
    1. Abstract
    2. Nanoparticles’ Use in Pharmacokinetics
    3. Nanoparticles as Diagnostic Imaging Tools
    4. Nanoparticles as a Theranostic Tool
    5. Nanoparticles as a Treatment Tool
    6. Conclusions
    7. References
  13. Chapter 4. Surgical implications of surface texturing in breast implants
    1. Abstract
    2. Introduction
    3. Capsular Contraction
    4. The Cellular Response to Implant Surface Texturing
    5. The Textured Implant: History and Development
    6. The Silicone Shell
    7. Salt Loss Technique
    8. Stamping Technique
    9. Surface Texturing and Cellular Ingrowth
    10. Utility of Nanotechnology
    11. Three-Dimensional Surface Printing
    12. Surface Nanoparticles and Infection Prevention
    13. Conclusion
    14. References
  14. Chapter 5. Nanoscale engineering of silk fibroin scaffold architecture to repair patient-specific cancer defects
    1. Abstract
    2. Introduction
    3. Materials and Methods
    4. Results
    5. Discussion
    6. Conclusion
    7. Acknowledgments
    8. References
  15. Chapter 6. Magnetic nanoparticles and cancer
    1. Abstract
    2. Introduction
    3. Magnetic Drug Targeting
    4. Hyperthermia
    5. Magnetic Resonance Imaging
    6. References
  16. Chapter 7. Nanotechnology in neurosurgical oncology
    1. Abstract
    2. Background
    3. Chemotherapy
    4. Radiotherapy
    5. Surgery
    6. Novel Therapies
    7. Challenges
    8. Future Directions
    9. References
  17. Chapter 8. Nanotechnologies for brain tumor therapy
    1. Abstract
    2. Overview on Brain Gliomas
    3. Blood–Brain Barrier
    4. Nanoparticles
    5. Conclusion and Critical Issues
    6. References
  18. Index