October 2016
Intermediate to advanced
218 pages
7h 18m
English
L.W. Dunne, T.S. Iyyanki, C.E. Butler and A.B. Mathur, The University of Texas MD Anderson Cancer Center, Houston, TX, United States
Bombyx mori silk fibroin (SF)-based scaffolds were engineered by modulating SF solution parameters. Three-dimensional (3D) scaffolds were fabricated, and microstructure and mechanical properties were characterized. Silk solution parameters of SF scaffolds such as SF solution concentration (0.91–3.33% (w/v)), filter size (0.22, 0.45, 100 µm), pH (4, 5.5, 7.4), and ion concentration (no PBS, 0.1× PBS, 1× PBS) were altered. SF solution particle size was measured using dynamic light scattering (DLS); ...