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Nanotechnology in Cancer
book

Nanotechnology in Cancer

by Anshu Mathur
October 2016
Intermediate to advanced content levelIntermediate to advanced
218 pages
7h 18m
English
Elsevier
Content preview from Nanotechnology in Cancer
Chapter 5

Nanoscale engineering of silk fibroin scaffold architecture to repair patient-specific cancer defects

L.W. Dunne, T.S. Iyyanki, C.E. Butler and A.B. Mathur,    The University of Texas MD Anderson Cancer Center, Houston, TX, United States

Abstract

Bombyx mori silk fibroin (SF)-based scaffolds were engineered by modulating SF solution parameters. Three-dimensional (3D) scaffolds were fabricated, and microstructure and mechanical properties were characterized. Silk solution parameters of SF scaffolds such as SF solution concentration (0.91–3.33% (w/v)), filter size (0.22, 0.45, 100 µm), pH (4, 5.5, 7.4), and ion concentration (no PBS, 0.1× PBS, 1× PBS) were altered. SF solution particle size was measured using dynamic light scattering (DLS); ...

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Publisher Resources

ISBN: 9780323390811