Chapter 3

Animal models in cancer nanotechnology

S.L. Craig1 and V.B. Jensen2,    1Medical University of South Carolina, Charleston, SC, United States,    2The University of Texas MD Anderson Cancer Center, Houston, TX, United States

Abstract

To better understand disease processes, living organisms are still required. Animals make good research subjects since they are susceptible to many of the same health problems, may be genetically manipulated to mimic human disease conditions, and their living environment may be controlled to provide a consistent research outcome.

Nanoscience studies ultrasmall structures, usually 0.1–100 nm, whereas nanotechnology is the science of manipulating these small structures. Nanoparticles are used as diagnostic ...

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