Carbon Nanomaterials for Bioimaging, Bioanalysis, and Therapy
by Yuen Y. Hui, Huang-Cheng Chang, Haifeng Dong, Xueji Zhang
6 Tracking Photoluminescent Carbon Nanomaterials in Biological Systems
Simon Haziza1,2 Laurent Cognet3,4 and François Treussart5
1 James H. Clark Center for Biomedical Engineering & Sciences, Stanford University, USA
2 CNC Program, Stanford University, USA
3 Laboratoire Photonique Numérique et Nanosciences, Université de Bordeaux, Talence, France
4 Institut d'Optique d’Aquitaine & CNRS, Talence, France
5 Laboratoire Aimé Cotton, CNRS, Université Paris‐Sud, ENS Paris‐Saclay and Université Paris‐Saclay, Orsay, France
Chapter Summary
This chapter highlights some recently published outstanding researches that have pushed further the boundary of photoluminescent carbon nanomaterials applications to biological systems and have brought invaluable insights into cellular and organism dynamics. From our perspective, there is a need for nanoparticle‐based methodologies that allow researchers to access the spatiotemporal dynamics inherent to a wide variety of biological processes.
Two carbon allotropes have recently shown remarkable advances in neurosciences: fluorescent nanodiamonds (FND) [1], and single‐walled carbon nanotube (SWCNT) [2]. This chapter highlights three examples of recent archetypical achievements based on the tracking of FND or SWCNT while being aware that the list is not exhaustive. Single‐particle tracking (SPT) of FND was used to monitor the endosomal transport inside hippocampal neurons dissociated from mouse embryos and the author used this nanoparticle‐based ...