Skip to Main Content
Carbon Nanomaterials for Bioimaging, Bioanalysis, and Therapy
book

Carbon Nanomaterials for Bioimaging, Bioanalysis, and Therapy

by Yuen Y. Hui, Huang-Cheng Chang, Haifeng Dong, Xueji Zhang
January 2019
Beginner to intermediate content levelBeginner to intermediate
376 pages
14h 35m
English
Wiley
Content preview from Carbon Nanomaterials for Bioimaging, Bioanalysis, and Therapy

10 Functionalized Carbon Nanomaterials for Drug Delivery

Naoki Komatsu

Graduate School of Human and Environmental Studies, Kyoto University, Japan

10.1 Introduction

Chemical functionalization of nanomaterials is important to control their physical properties [1, 2]. Since their applications frequently require the homogeneity in the physical properties of the components, many precise functionalization methods for nanomaterials have been developed in view of their applications from electronics and optics to biomedicine.

Nanomedicine has been attracting growing interest in terms of therapy and diagnosis, or so called theranostics. In the field, nanomaterials play a key role and hence they are chemically functionalized frequently to meet the requirements for the purpose [3]. In the nanomaterial‐based drug delivery system (DDS), for example, the following functions are required: the nanodrug has to disperse well in the blood to avoid embolism; circulate throughout the body to avoid leaking from the pores in the blood vessel and trapping in the reticuloendothelial system; accumulate in the targeting organ or tissue; and finally, release the loaded drug.

Among the nanomaterials in the DDS, carbon nanomaterials have the following characteristic properties: (i) basically inert, but functionizable at the functional groups such as carboxylic and hydroxyl ones on the surface, edge, and defect through organic transformation; (ii) variety of options in terms of shapes including ...

Become an O’Reilly member and get unlimited access to this title plus top books and audiobooks from O’Reilly and nearly 200 top publishers, thousands of courses curated by job role, 150+ live events each month,
and much more.
Start your free trial

You might also like

Carbon-Based Metal-Free Catalysts, 2 Volumes

Carbon-Based Metal-Free Catalysts, 2 Volumes

Liming Dai
Fluorescent Nanodiamonds

Fluorescent Nanodiamonds

Huan-Cheng Chang, Wesley Wei-Wen Hsiao, Meng-Chih Su
Nanotechnology Applications for Clean Water

Nanotechnology Applications for Clean Water

Mamadou Diallo, Jeremiah Duncan, Nora Savage, Anita Street, Richard Sustich

Publisher Resources

ISBN: 9781119373452Purchase book