Chapter 11Plasmonic Nanopores: A New Approach Toward Single Molecule Detection

Gaurav Khandelwal1, Sima Umrao2, Narsingh R. Nirala3, Sadhana S. Sagar4 and Vinod Kumar5*

1Indian Institute of Technology Delhi, Hauzkhas, New Delhi, India

2School of Electronics and Electric Engineering, Sungkyunkwan University (SKKU), Suwon, Korea

3School of Materials Science and Technology, IIT (BHU), Varanasi, India

4Rani Lakshmi Bai Central Agricultural University, Jhansi, India

5Department of Materials Engineering, Ben Gurion University of the Negev, Beer-Sheva, Israel

*Corresponding author: mail2vinod2@gmail.com, vinod@post.bgu.ac.il

Abstract

In recent years nanopores technology have been widely explored for single molecular detection of biomolecules. An integration of optical modalities with ionic current signals have found to be an attractive approach to receive more accurate information about target analyte. Assimilation of plasmonic detection with electrical read out signals of solid state nanopores has configured a new approach known as Plasmonic nanopores. Optical signals will help to reveal chemical states and properties of the specific analytes inside the nanopores with potential of multiplexed detection by multi-nanopore. Plasmonic nanopores hold immense possibilities for developing efficient sensing devices and thorough investigations are needed. The proposed book chapter will provide a detailed information about the fabrication of plasmonic nanopores, their recent application in ...

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