Producing High-Quality Figures Using SAS/GRAPH and ODS Graphics Procedures

180 Producing High-Quality Figures Using SAS/Graph

®

and ODS Graphics

10.3.2.1 First Part Main Sections and Features

10.3.2.1.1 Dataset Simulation

An IOP dataset is simulated to include 518 subjects, with each subject ran-

domly assigned to one of the 8 sites and to either Drug A or Drug B at a 1:1

ratio at each site. IOP values are assigned based on baseline and post-baseline

visit and hours, with no expected difference between the two treatment

groups at all visits and hours.

10.3.2.1.2 Data Analyses and Manipulation

• The IOP change from baseline is calculated for post-baseline visits

and hours.

• The estimated LS mean and its 95% CI are derived ...