Emerging Nanotechnologies in Dentistry

Chapter 3. Antimicrobial Nanoparticles in Restorative Composites

N. Beyth, I. Yudovin-Farber, E.I. Weiss and A.J. Domb

The Hebrew University of Jerusalem, Jerusalem, Israel

Contents

3.1 Introduction 35

3.2 Antibacterial Restorative Composites 36

3.2.1 Filler Phase Modification 36

3.2.1.1 Released Antibacterial Agents 36

3.2.1.2 Nonreleased Antibacterial Agents 37

3.2.2 Matrix Phase Modification 37

3.2.2.1 Released Antibacterial Agents 37

3.2.2.2 Nonreleased Antibacterial Agents 38

3.3 Antimicrobial Macromolecules 38

3.3.1 Polycationic Disinfectants 38

3.3.2 Polyethyleneimine 39

3.4 Nanoparticles 40

3.4.1 Polyethyleneimine Nanoparticles 40

3.4.1.1 Synthesis 40

3.4.1.2 Characterization 41

3.4.1.3 Incorporation of Polyethyleneimine Nanoparticles 43

3.5 Conclusions ...