High Value Manufacturing: Advanced Research in Virtual and Rapid Prototyping

mechanical equilibrium modulus and dynamic stiff-

ness (approaching that of human cartilage). Six weeks

after in vivo implantation, femoral and tibial con-

structs had integrated with rabbit bone and partial joint

function had been regained. However, repair tissue

after appeared fibrocartilage-like and did not resem-

ble implanted cartilage, suggesting degeneration of

the initial hyaline-like structure implanted (Woodfield

et al., 2009).

Hendriks et al. (2013) optimized poly(ethylene

oxide-terephtalate)/(butylene-terephtalate)) PEOT/

PBT composition, porosity and pore orientation to

produce structures that would initially closely match

native cartilage mechanical demands. Results showed

enhanced hyaline cartilage regeneration, with con-

structs matching ...