September 2013
Intermediate to advanced
650 pages
34h 25m
English
book
High Value Manufacturing: Advanced Research in Virtual and Rapid Prototyping
by Paulo Silva Bartolo, Ana Cristina Soares de Lemos, Antonio Mario Henriques Pereira, Artur Jorge Dos Santos Mateus, Catarina Ramos, Cyril Dos Santos, David Oliveira, Elodie Pinto, Flavio Craveiro, Helena Galha Bartolo, Henrique Amorim Almeida, Ines Sousa, Joao Manuel Matias, Lina Durao, Miguel Gaspar, Nuno Manuel Fernandes Alves, Pedro Carreira, Telma Ferreira, Tiago Marques
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High Value Manufacturing – Bártolo et al. (Eds)
© 2014 Taylor & Francis Group, London, ISBN 978-1-138-00137-4
Levodopa controlled release from alginate membranes
M.R. Franco, S. Biscaia, T. Viana & P. Bártolo
Centre for Rapid and Sustainable Product Development, Polytechnic Institute of Leiria, Portugal
ABSTRACT: L-Dopa (LD), the hydroxyphenylalanine levogyre enantiomer, is still reported as the gold stan-
dard drug when we consider Parkinson Disease (PD) therapeutics. However, this molecule undergoes a massive
methabolisation in the Gastro-Intestinal-Tract (GIT) by the Aromatic Aminoacid Descarboxylase (AADC)
enzyme. In this study, we aimed to develop a transdermic and controlled delivery of the drug in order to
provide a higher bioavailability
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I wanted to learn C and C++, but it didn't click for me until I picked up an O'Reilly book. When I went on the O’Reilly platform, I was astonished to find all the books there, plus live events and sandboxes so you could play around with the technology.Addison B.
I’ve been on the O’Reilly platform for more than eight years. I use a couple of learning platforms, but I'm on O'Reilly more than anybody else. When you're there, you start learning. I'm never disappointed.Amir M.
I'm always learning. So when I got on to O'Reilly, I was like a kid in a candy store. There are playlists. There are answers. There's on-demand training. It's worth its weight in gold, in terms of what it allows me to do.