Chapter 1: Introduction to drug discovery

Stephanie Kay Ashenden    Data Sciences and Quantitative Biology, Discovery Sciences, R&D, AstraZeneca, Cambridge, United Kingdom

Abstract

The drug discovery and development process (here meaning the pharmaceutical research and development pipeline from concept to beyond the patient) is a long, expensive, and complex process; only a small proportion of molecules that are identified as a candidate drug are approved as new drugs each year. It has been estimated that it costs approximately US$2.6 billion to develop a new treatment. In addition to creating a finished product costing over $1 billion, it can take up to 15 years. The production of novel drugs that are approved by the FDA has not increased ...

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