Bioinformatics and Biomedical Engineering: New Advances

Bioinformatics and Biomedical Engineering – Chou & Zhou (Eds)

© 2016 Taylor & Francis Group, London, ISBN 978-1-138-02784-8

91

Degree distribution of protein-protein interaction

networks formed by gene duplication

Z. Ma & H. Xu

Department of Electrical and Computer Engineering, University of Waterloo, Waterloo, ON, Canada

X.G. Wu

Department of Electrical Engineering, Stanford University, Stanford, CA, USA

ABSTRACT: This paper proposes a degree distribution function for protein-protein inter-

action networks. It is derived from modeling the protein-protein interaction network as a

random duplication graph with sparse initial state, where the duplication particularly refers

to the gene duplication that produces new proteins and grows the network. This ...