198
measurement means of retinal lesion evolution. These final results are accepted by the clinical
ophthalmologists.
4 CONCLUSION
To monitor pathological varying tendency, we have developed a computer-aided lesion
change detection and quantitative measurement changed areas system. Our method is more
straightforward and works better than other state-of-the-art techniques. Experimental results
show that it is effective in detecting changes (especially identifying small and weak variations)
in longitudinal retinal images.
ACKNOWLEDGMENTS
This work was supported in part by Shanghai Jiao Tong University College Students’ Innova-
tive Practice (IPP10090) and the National Natural Science Foundation of China (31375020).
The authors would like to thank ...