
5
Health economic evaluation in practice
5.1 Introduction
In this final chapter we present some examples of health economic evaluation.
In particular we focus on three “typical” cases; the first concerns the analysis
of individual level data, specifically from a RCT, in which a sample of individ-
uals is observed in terms of the relevant measures of cost and clinical outcome.
The second example focusses on the process of evidence synthesis, a situation
particularly relevant when individual data are not available. In these situa-
tions, the relevant random quantities can be estimated by the combination of
the available evidence, e.g. coming from published ...