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Bioinformatics for Biomedical Science and Clinical Applications by K-H Liang

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4

Proteomics

Abstract:

Proteomics is the varieties, quantities, roles and dynamics of all proteins in a cell, tissue or organism. Proteins are structural or functional elements of cells, comprising sequences of amino acids assembled according to templates of DNA and RNAs. Their sequences determine their structure, thus their cellular functions. Post transcriptional modifications occur in most proteins. Protein dynamics result from synthesis and degradation, which are well controlled in normal physiology. They also work in groups, so concurrent expressions, localization and physical interactions can shed light on their cellular roles. Proteins can function in extracellular space, circulating via the blood stream to function far away from where ...

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