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Bioinformatics for Biomedical Science and Clinical Applications by K-H Liang

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5

Systems biomedical science

Abstract:

Cells seldom live in isolation. They constantly interact with ambient cells and the environment. Many conventional studies have focused on particular molecular activities taking place within cells, which are cultured in artificial environments, so the rich interaction between the cells and their natural environment is unexplored. To acquire a more complete picture, systematic investigation of all cellular activities in different environmental settings would be valuable. With three distinct omics (genomics, transcriptomics and proteomics), we will see how new insights into human biology can be approached by systematic hypothesis generation and panoramic, multi-scale data filtering, integration and modeling. ...

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