June 2023
Intermediate to advanced
460 pages
6h 20m
Japanese
Content preview from Pythonではじめるバイオインフォマティクス ―可読性・拡張性・再現性のあるコードを書くために
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3章
DNAの逆相補鎖配列への変換：文字列の操作
Rosalind REVCチャレンジ（https://oreil.ly/ot4z6）では、DNAの塩基はA-TとG-Cのペアを形成していると説明されています。また、DNAには方向性があり、通常は5’末端（5プライムエンド）から3’末端（3プライムエンド）に向かって読みます。DNAの逆相補配列とは、逆方向（3’末端から5’末端方向）から読んだ相補配列のことです。例えば、図3-1で示すようにDNA塩基配列AAAACCCGGTの相補配列はTTTTGGGCCAです。この配列を逆にして（3’末端から5’末端方向に読んで）、得られる配列ACCGGGTTTTがAAAACCCGGTの逆相補配列です。
図3-1 DNAの逆相補配列とは、逆方向（3’末端から5’末端方向）から読んだ相補配列のことである
DNAの逆相補配列を得るための方法はたくさんあります。最終的にはBiopythonライブラリの関数を使用しますが、Pythonをより理解するために、独自のアルゴリズムも考えてみましょう。
この章では以下のことを学びます。
- 辞書の検索機能を用いて決定木（決定の分岐条件）を実装
- リストや文字列を動的に生成
- イテレータの一例である
reversed()関数の使い方 - Pythonでの文字列とリストの扱い方
- リスト内包表記
str.maketrans()とstr.translate()を使った文字列変換- Biopythonの
Bio.Seqモジュールの使い方 ...
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I'm always learning. So when I got on to O'Reilly, I was like a kid in a candy store. There are playlists. There are answers. There's on-demand training. It's worth its weight in gold, in terms of what it allows me to do.