Computation in BioInformatics
by S. Balamurugan, Anand T. Krishnan, Dinesh Goyal, Balakumar Chandrasekaran, Boomi Pandi
11Bioinformatics in Cancer Detection
Mohit Sharma1,2, Umme Abiha3, Parul Chugh3, Balakumar Chandrasekaran4 and Nikhil Agrawal5*
1Post Graduate School of Molecular Medicine, Medical University of Warsaw, Warsaw, Poland
2Malopolska Centre of Biotechnology, Jagiellonian University, Krakow, Poland
3Amity Institute of Biotechnology, Noida, India
4Faculty of Pharmacy, Philadelphia University-Jordan, Amman, Jordan
5College of Health Sciences, University of KwaZulu-Natal, Westville, Durban, South Africa
Abstract
The uncontrolled growth of abnormal cells is generally determined by the alterations in genes and epigenetic factors. Oncological research is undergoing a drastic revolution due to advanced technology improvement in the verge of exploring the relationship of molecules which make a unit cell of an organism. Molecular biologists are more aware about the genomic, transcriptomic, and proteomic data because of the obvious technology advancement in the area of molecular medicine. This has further lead to the development of novel potential targets for drug development and also establishment of molecular markers for unified treatment and therapy against cancer. Numerous cancer studies have been carried out using altered protocols, samples, and data from multiple sources in order to compare and validate new strategies with the conventional ones. Moreover, it also opens a wide arena to develop personalized or stratified medicine to counter medicinal upheaval. Bioinformatics helps to develop ...
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