Computation in BioInformatics

Preface

The past couple of years will be remembered for the COVID-19 pandemic and ensuing lockdowns, wherein almost every country saw a series of lockdowns and consequent suffering. To overcome the pandemic, the discovery of vaccines and other alternative therapies were attempted worldwide. Currently, the discovery of new solutions to the pandemic can be facilitated through the use of promising bioinformatics techniques and integrated approaches. Hence, this book provides readers with an understanding of the use of bioinformatics tools in new drug design and the discoveries which are inevitable in the present situation. The book covers a broad spectrum of the bioinformatics field, starting with the basic principles, concepts, and application areas under multidisciplinary sections. Also covered is the role of bioinformatics in drug design and discovery, including aspects of molecular modeling. Some of the chapters provide detailed information on bioinformatics-related topics, such as silico design, protein modeling, DNA microarray analysis, DNA-RNA barcoding, and gene sequencing, all of which are currently needed in the industry. Also included are specialized topics, such as bioinformatics in cancer detection, genomics and proteomics, which are highly relevant to the present scenario. Moreover, a few chapters explain highly advanced topics, like machine learning and covalent approaches to drug design and discovery, all of which are significant in pharma and biotech research and ...