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Essentials of Molecular Biology by Malathi V.

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1

Nucleic Acids

CONCEPT OUTLINE
  • Introduction
  • DNA and RNA as Genetic Materials
    • DNA
    • RNA
  • Structure of Nucleic Acids
    • The chemical nature of DNA and RNA
    • Keto-Enol tautomerism of the nitrogenous bases
    • Nucleosides
    • Pyrimidines exist entirely in the anti-conformation
    • Chargaff rule
    • Nucleotides
    • The primary structure of DNA
    • Watson and Crick model of DNA – secondary structure of DNA
    • The DNA grooves
    • DNA conformations
    • B-DNA
    • A-DNA
    • Z-DNA
    • Triple standard DNA
    • Cruciforms or Holliday junction
    • Tertiary structure
  • Properties of the DNA
    • Physical properties of the DNA
    • Chemical stabibility of nucleic acids
  • DNA Topology
    • Linking, twisting and writhing
    • Topoisomerases
  • Types of RNA
  • Types of DNA
    • The chromosomal DNA
    • The autosomal DNA
    • Y-DNA
    • Mitochondrial DNA (mtDNA) ...

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