6

Protein Sorting

CONCEPT OUTLINE
  • Introduction
  • Signal Sequences
  • Tanslocation of Secretory Proteins Across the ER
    • The signal sequences of secretory proteins to ER
    • The signal recognition particle
    • SRP receptor
    • Translocation into the ER lumen
    • Insertion of proteins into the ER membrane
    • GPI-anchored proteins
  • Protein Modifications in the ER
    • Protein glycosylation
    • Disulphide bond formation
    • The role of N-linked glycosylation in ER protein folding
  • Protein Targeting to Mitochondria and Chloroplast
    • Transport of proteins to mitochondria
    • Transport of proteins to chloroplast
  • Protein Targeting to the Nucleus
    • Nuclear localization signals
    • Transport of proteins into the nucleus
    • Transport of proteins out of the nucleus
    • Transport and Sorting of Proteins ...

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