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Essentials of Molecular Biology by Malathi V.

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5

Translation

CONCEPT OUTLINE
  • Introduction
  • Genetic Code
    • Codons

       

  • Deciphering the Genetic Code
    • Nirenberg and Khorana experiment

       

  • Characteristic Features of the Genetic Code
    • The mitochondrial genetic code

       

  • Wobble Hypothesis
    • Codon—anticodon interactions
    • Wobble hypothesis
  • Ribosome Structure
    • Prokaryotic ribosome—70S ribosome
    • Self-assembly of ribosomes
    • Eukaryotic ribosome—80S ribosome
  • Protein Synthesis in Prokaryotes
    • Activation of the amino acids
    • The two classes of aminoacyl-tRNA synthetases
    • Aminoacyl-tRNA synthetases and proof reading
    • tRNA molecule acts as adaptors
    • The interaction between aminoacyl-tRNA synthetases and tRNA constitutes a second genetic code
    • Polypeptide synthesis begins at the amino-terminal end
    • The process of translation ...

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