September 2015
Intermediate to advanced
292 pages
8h 43m
English
Content preview from Accelerating Discovery
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164 ◾ Accele rating Dis cover y
IBM WATSON
IGF2BP2, which was provided in
the initial pool of T2D genes, is
linked to SLC30A8 through IFNG,
a gene that was not in the initial
pool.
e proteins encoded by
IGF2BP2, SLC30A8, and
MTNR1B (also not in the initial
pool) all impact the protein product
of IFNG (in the same or separate
pathways).
e cluster offers new genes to
study that may otherwise not
have been known to impact
SLC30A8.
Common genetic variants differentially influence
the transition from clinically defined states
of fasting glucose metabolism
G. A. Walford · T. Green· B. Neale · T. Isakova · J. L. Rotter · S. F. A. Grant ·
C. S. Fox · J. S. Pankow · ...
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