June 2018
Beginner to intermediate
304 pages
7h 38m
Korean
Content preview from 우아한 사이파이: 수학, 과학, 엔지니어링을 위한 파이썬 데이터 분석 라이브러리 SciPy
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54
우아한 사이파이
x
축에
y
레이블이 부여된다. 이것은 분명한 순서가 없는 선택적 매개변수의 평범한 시그니처
signature
오류다.
이제 유전자 길이와 수를 계산한다.
log
_
counts
=
np
.
log
(
counts
_
lib
_
norm
+
1
)
mean
_
log
_
counts
=
np
.
mean
(
log
_
counts
,
axis
=
1
) # 샘플 평균
log
_
gene
_
lengths
=
np
.
log
(
gene
_
lengths
)
with
plt
.
style
.
context
('
style
/
thinner
.
mplstyle
'):
binned
_
boxplot
(
x
=
log
_
gene
_
lengths
,
y
=
mean
_
log
_
counts
)
유전자가 길수록 유전자 수가 더 많다는 것을 다음 그림에서 알 수 있다. 이것은 데이터를 분석
하여 얻은 기술적인 결과물이다. 이것을 어떻게 설명할 수 있을까?
유전자 길이(
log
)
평균 개수(
log
)
1.4.4
샘플과 유전자의 정규화 :
RPKM
RNA
염기서열분석 데이터의 가장 간단한 정규화 방법 중 하나는
RPKM
이다.
RPKM
은 샘플
과 유전자에 의해 정규화되는 아이디어를 종합한 방식이다.
RPKM
을 계산할 때 개체 공간의
크기(각 열의 합 )와 유전자 길이 모두를 정규화한다.
RPKM
계산에 사용되는 값은 다음과 같다.
●
C
= 매핑된 유전자의 판독 수
●
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O’Reilly covers everything we've got, with content to help us build a world-class technology community, upgrade the capabilities and competencies of our teams, and improve overall team performance as well as their engagement.Julian F.
I wanted to learn C and C++, but it didn't click for me until I picked up an O'Reilly book. When I went on the O’Reilly platform, I was astonished to find all the books there, plus live events and sandboxes so you could play around with the technology.Addison B.
I’ve been on the O’Reilly platform for more than eight years. I use a couple of learning platforms, but I'm on O'Reilly more than anybody else. When you're there, you start learning. I'm never disappointed.Amir M.
I'm always learning. So when I got on to O'Reilly, I was like a kid in a candy store. There are playlists. There are answers. There's on-demand training. It's worth its weight in gold, in terms of what it allows me to do.