Bioinformatics with Python Cookbook - Second Edition

Working with high-quality reference genomes

In this recipe, you will learn about a few general techniques to manipulate reference genomes. As an illustrative example, we will study the GC content—the fraction of the genome that is based on guanine-cytosine in Plasmodium falciparum, the most important parasite species that causes malaria. Reference genomes are normally made available as FASTA files.