Bioinformatics with Python Cookbook - Second Edition

Getting ready

In keeping with the malaria theme, we will use the reference genomes of two mosquitoes that are vectors of malaria: Anopheles gambiae (which is the most important vector of malaria and can be found in sub-Saharan Africa) and Anopheles atroparvus, a malaria vector in Europe (while the disease has been eradicated in Europe, this vector is still around). The A. gambiae genome is of reasonable quality. Most chromosomes have been mapped, although the Y chromosome still needs some work. There is a fairly large unknown chromosome, probably composed of bits of X and Y chromosomes, as well as midgut microbiota. This genome has a reasonable amount of positions that are not called (that is, you will find Ns instead of ACTGs). The A. atroparvus ...