Bioinformatics with Python Cookbook - Second Edition

Dealing with low-quality genome references

Unfortunately, not all reference genomes will have the quality of P. falciparum. Apart from some model species (for example, humans, or the common fruit fly Drosophila melanogaster) and a few others, most reference genomes could use some improvement. In this recipe, we will look at how to deal with reference genomes of lower quality.