
240 Discrete Event Simulation for Health Technology Assessment
values can be used in predictive equations to ensure times to events, physi-
ologic changes, and costs, and other responses are the same except for any
intervention-specic parameters. It is important to note, however, that this
resemblance holds only immediately after duplication—the duplicated enti-
ties are only identical at that point, but not necessarily throughout the simu-
lation unless something is done to ensure that their experiences unrelated to
the intervention are also made to match.
7.1.2 Duplication of Pathways
Another form of duplication relates to events experienced w ...