Chapter 17Astaxanthin: Current Advances in Metabolic Engineering of the Carotenoid
Manmeet Ahuja, Jayesh Varavadekar, Mansi Vora, Piyush Sethia, Harikrishna Reddy and Vidhya Rangaswamy*
High Value Chemicals, Breakthrough R & D, Reliance Industries Limited. Reliance Corporate Park. Thane Belapur Road, Ghansoli, Navi Mumbai, (India)
*Corresponding author: Vidhya.Rangaswamy@ril.com
Abstract
Astaxanthin is a valuable carotenoid, naturally produced by some yeast and algae. It has significant biological properties. The molecule is available in synthetic and natural form. The increasing market demand and preference for biological astaxanthin provides an impetus for exploration in this area. This chapter discusses the recent progress made in production and fermentation from the natural producers Phaffia rhodozyma and Hematococcus pluvialis. This chapter also covers in detail the current state of the art in metabolic engineering of organisms including plants, bacteria, algae and yeasts to produce astaxanthin biologically.
Keywords: Astaxanthin, carotenoid, biological production, metabolic engineering
17.1 Introduction
Over the last decade, the family of carotenoids has received a lot of interest due to their potential health benefits in decreasing the risk of diseases relating to heart and eye, and cancer [1, 2]. Carotenoids or terpenoids are a class of more than 750 naturally occurring pigments which are produced by plants, algae as well as some bacteria and fungi; the majority of ...
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