Methods of Non-a-Amino Acid Synthesis, 2nd Edition

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7

Aminocyclic

andHeterocyclic

Amino Acids

This chapter will discuss cycloalkanes that have an amino group and a carboxyl

group on the ring or attached to a ring via pendant alkyl units. The place to begin a

discussion of such molecules is perhaps with the three-, four-, ve-, and six-mem-

bered ring derivatives. Of the two possible cyclopropaneamino acids, the 1-amino

derivative is an α-amino acid, but 1 is a β-amino acid. Apart from the α-amino

acid, there are two non-α-amino acid structures for aminocyclobutanoic acids, 2

(2-aminocyclobutane-1-carboxylic acid) and 3 (3-aminocyclobutane-1-carboxylic

acid). The non-α-amino acid cyclopenta ...