Biomaterials 175
they do not have even fair mechanical properties, where tensile strength, brittleness,
fracture toughness and resistance to wear are concerned. Thus, the HA coatings on
metallic implants forms a macro-composite material that can be used for clinical
applications, which combines of strength of metallic substrate and compatibility of
HA. Such composite provides natural xation of insert to bone and reduces adverse
effect due to release of metallic ions. Furthermore, HA coatings have been reported
to promote early bone formation around implants and promote the deposition and
differentiation of mesenchymal cells into osteoblasts on HA-coated implant surface
(Cleries et al., 2000). Ability to osteoblast adhesion onto the sur ...