You can open System Preferences in dozens of ways:
Choose its name from the menu.
Jump directly to a System Preferences pane by pressing Option as you tap keys on the top row of your keyboard: Option- for Mission Control preferences, Option-volume key (, , or ) for Sound prefs, Option-brightness keys ( or ) or Option-keyboard-brightness key ( or ) for the Displays prefs. At that point, you can click Show All or press ⌘-L to see the full spread.
If you know the name of the System Preferences panel you want, it’s often quicker to use Spotlight. To open iCloud Photos, for ...