10.4. Crossover Design Studies
Conditional logistic regression is a useful technique in the analysis of the crossover design study, also called the changeover study. In these designs, often used in clinical trials, the study is divided into periods and patients receive a different treatment during each period. Thus, the patients act as their own controls. Interest lies in comparing the efficacy of the treatments, adjusting for period effects and carryover effects. The basic crossover design is a two-period design, but designs with three or more periods are also implemented. This section describes the use of conditional logistic regression for both two- and three- period designs.
10.4.1. Two-Period Crossover Design
A two-period crossover study ...
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