August 2009
Intermediate to advanced
648 pages
17h 35m
English
book
Categorical Data Analysis Using The SAS® System, 2nd Edition
by Maura E. Stokes, Charles S. Davis, Gary G. Koch
Content preview from Categorical Data Analysis Using The SAS® System, 2nd Edition
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11.2. Estimating Tolerance Distributions
Table 11.1 displays data from an experiment in which animals were exposed to bacterial challenges after having one-quarter of their spleen removed (splenectomy). After 96 hours, their survival status was assessed. The stimulus is the bacterial challenge, and interest lies in assessing the tolerances of the animals’ immune systems to the bacterial challenge after they have had partial splenectomies (Koch and Edwards 1985).
| Status | ||
|---|---|---|
| Bacterial Dose | Dead | Alive |
| 1.2 × 103 | 0 | 5 |
| 1.2 × 104 | 0 | 5 |
| 1.2 × 105 | 2 | 3 |
| 1.2 × 106 | 4 | 2 |
| 1.2 × 107 | 5 | 1 |
| 1.2 × 108 | 5 | 0 |
In bioassay analysis, you make the assumption that responses of subjects are determined through a tolerance distribution. This means that ...
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