January 2013
Intermediate to advanced
148 pages
4h 22m
English
Content preview from Computational Neuroscience
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Preface v
Abbreviations xi
I. Nerve Fibres 1
Myelinated Axons 1
Demyelinating Neuropathies 7
Charcot-Marie-Tooth Diseases (CMT) and Type 1A (CMT1A) 8
Chronic Infl ammatory Demyelinating Polyneuropathy 9
(CIDP) and its Subtypes
Guillain-Barré Syndrome (GBS) and Multifocal Motor 10
Neuropathy (MMN)
Neuronopathies 11
Amyotrophic Lateral Sclerosis (ALS) 11
Axonal Excitability 12
Mathematical Modeling of Nerve Fibres 14
II . Models and Methods for Investigation of the Human 18
Motor Nerve Fibre
Multi–Layered and Double Cable Models 18
Line-Source Model 28
Methods of Stimulation and Calculation of the Potentials 30
(Action, Electrotonic and Extracellular)
Methods for Calculation of the Strength-Duration Time 32
Constants, ...
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