January 2013
Intermediate to advanced
148 pages
4h 22m
English
Content preview from Computational Neuroscience
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Multi–Layered and Double Cable Models
The method of mathematical modeling and computational
simulations of human motor nerve fi bres in normal and abnormal
cases are generally used to reveal some of the mechanisms
underlying nerve excitability abnormalities observed and recorded
in patients with demyelinating neuropathies and neuronopathies.
The simulations presented here apply our model (Stephanova
2001), in which 150 interconnected parallel lamellae are simulated
by alternating 150 lipid and 150 aqueous layers within the myelin
sheath. The aqueous layers provide appreciable longitudinal and
radial conductance, the latter via a spiral pathway ...
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I'm always learning. So when I got on to O'Reilly, I was like a kid in a candy store. There are playlists. There are answers. There's on-demand training. It's worth its weight in gold, in terms of what it allows me to do.