114 Computational Neuroscience: Simulated Demyelinating Neuropathies and Neuronopathies
the objective study of mechanisms in hereditary and chronic
demyelinating neuropathies, but also have a predictive value.
Results also show that when the reduction value is under 70%
the effect of the myelin sheath aqueous layers on the excitability
membrane properties is negligible for all investigated subtypes.
We suggest that the effect of the aqueous layers on the excitability
properties of the simulated GBS and MMN will also be negligible,
as the excitability property changes in the focally demyelinated
subtypes are vastly smaller than those in the systematically
demyelinated subtypes. However, even differences of 1−3%, as a
result of the effect of ...