For the vast majority of Python users in Windows, PythonWin will never be more than an interesting IDE environment for developing Python applications. But many other Windows developers are beginning to use PythonWin to develop Windows applications. When comparing the three GUI toolkits available in this book, you will probably come to the conclusion that PythonWin is the least suitable for simple, small GUI applications written in Python, and this would be fair. However, depending on your particular circumstances (usually either because you have an existing MFC investment or it’s important to use some user-interface features offered only by PythonWin), it may be a good choice.
PythonWin suffers from a lack of decent documentation. A Windows help
file is included that contains a reference guide for all of the
objects and methods exposed by PythonWin, but PythonWin doesn’t
include a comprehensive overview of the MFC framework. There are many
good MFC books available, so a specific recommendation is impossible.
Information from Microsoft on MFC can be found at