Imaging 585
that can only withstand average powers of irradiation of a few mW, these noise
considerations limit the applicability of diffraction limited imaging to scattering
densities µ
s
L ≤ 35.
The multiply scattered photon path can be described by a diffusion model [20].
For L l
t
, it can be shown that a collimated input beam of diameter d < l
t
at the
sample input broadens to a diameter d
, which is approximately given by [21]:
d
= 0. 2L, (13.3)
if we refer to the early-arriving scattered light that exceeds the detection noise
and to illumination intensities below the critical values for biomedical samples.
The quantity d
gives a reasonable measure of the resolution that can be achieved
in imaging an object buried in a dense scatterer. With a sample ...