January 2015
Intermediate to advanced
412 pages
12h 10m
English
Content preview from Electrochemical Biosensors
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November 11, 2014 15:49 PSP Book - 9in x 6in 05-Serge-Cosnier-c05
140 Electrochemical Biosensors Based on Carbon Nanotubes and Nanohybrids
size on the CNT-FET using the fragment of an IgG antibody to make
the target approaching to CNTs (Fig. 5.3a). The results show that
CNT-FET biosensors using a whole antibody had very low sensitivity
(detection limit was ∼1000 ng/mL), whereas those based on small
fragments of IgG antibodies could detect 1 pg/mL (∼7fMlevel).
An immunosensor of mouse IgG was also accessible by monitoring
the electrical impedance change of a nanotube array electrode with
immobilized mouse IgG antibodies [115]. Aptamers can also replace ...
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