
November 7, 2014 13:15 PSP Book - 9in x 6in 09-Serge-Cosnier-c09
Conductometry in Enzyme Catalysis 257
9.2.1.4 Biosensor for testing protein denaturation
Proteomics technologies are a useful tool for the identification of
disease biomarkers. Many cellular changes in proteins expression,
as a response to an external stimulus or mutation, can be expressed
directly on the proteins’ sequence and structure. The amino acid
sequence constituting proteins is the exact expression of the
DNA sequence; a mutation on the encoding gene can induce the
appearance of new protein properties or a change in its activity.
One of these changes can be the appearance or disappearance ...